We use technology to unravel new microscale phenomena in non-excitable biological systems.
We address outstanding questions in biology to enable transformative technologies in healthcare.
We use technology to unravel new microscale phenomena in non-excitable biological systems.
We address outstanding questions in biology to enable transformative technologies in healthcare.
Our initial focus areas are cancer signalling, cancer cell migration, and their interplay.
We have many other goals to chase as we expand.
We aim at contributing to the understanding of electrical and mechanical signalling in cancer cells and cell networks, and their implications on the metastatic process. We aim at further manipulating electromechanical signalling in cancer for diagnostic and therapeutic purposes. In our current projects, we design interface platforms that can track the movements of breast cancer cells in vitro and measure their electrical and mechanical properties. We played a key role in driving the shift toward the use of micro/nano electrical systems beyond the recording of action potentials in excitable cells.
Our most recent releases in this area:
Vision on cancer signalling: R. Moreddu, Adv. Sci. 2024, 11, 2304110;
Cancer electric signalling recorded via microelectrodes: R. Melikov et al., biorXiv 2024;
On the clinical relevance of in vitro research: D. Dias et al., arXiv 2025;
Broader vision in technology: P. Cadinu et al., arXiv 2025;
Possible routes in computing: R. Moreddu & M. Levin, arXiv 2025.